The Lake Eyre Basin Coordinating Group is working to establish linkages with existing representative bodies in the Desert Rivers Region to ensure stakeholders of the area have a voice in the wider Lake Eyre Basin process.

The Desert Rivers Region contains representations of the following bioregions: Finke, MacDonnell, Burt Plain, Tanami, Mitchell Grass Downs, Channel Country, Simpson/Strzelecki Dunefields, and Stony Plains. It encompasses the Sandover River in the north along with the catchments of the Hay, Plenty, Hale, Todd and Finke rivers and most of the Simpson Desert.

This is the most hydrologically isolated region of the Lake Eyre Basin with none of its streams contributing to Lake Eyre on a regular basis. There are, however, indications that the Finke and Sandover rivers can join the main system during periods of extremely intense flooding. Anecdotal evidence suggests this occurred with the Finke flowing into the Macumba in the first decade of the 20th century and the Sandover flowing into the Georgina in mid 1980s.